1HUT
THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER
Summary for 1HUT
Entry DOI | 10.2210/pdb1hut/pdb |
Related PRD ID | PRD_000021 |
Descriptor | DNA 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3', ALPHA-Thrombin light chain, ALPHA-Thrombin heavy chain, ... (5 entities in total) |
Functional Keywords | thrombin, blood clotting, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 3 |
Total formula weight | 39070.77 |
Authors | Padmanabhan, K.,Padmanabhan, K.P.,Ferrara, J.D.,Sadler, J.E.,Tulinsky, A. (deposition date: 1993-05-27, release date: 1994-06-22, Last modification date: 2013-02-27) |
Primary citation | Padmanabhan, K.,Padmanabhan, K.P.,Ferrara, J.D.,Sadler, J.E.,Tulinsky, A. The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. J.Biol.Chem., 268:17651-17654, 1993 Cited by PubMed: 8102368PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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