1HUT

THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER

Summary for 1HUT

• Entry DOI: 10.2210/pdb1hut/pdb
• Related PRD ID: PRD_000021
• Descriptor: DNA 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3', ALPHA-Thrombin light chain, ALPHA-Thrombin heavy chain, ... (5 entities in total)
• Functional Keywords: thrombin, blood clotting, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 3
• Total formula weight: 39070.77

Authors

Padmanabhan, K.,Padmanabhan, K.P.,Ferrara, J.D.,Sadler, J.E.,Tulinsky, A. (deposition date: 1993-05-27, release date: 1994-06-22, Last modification date: 2013-02-27)

• Primary citation: Padmanabhan, K.,Padmanabhan, K.P.,Ferrara, J.D.,Sadler, J.E.,Tulinsky, A.; The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.; J.Biol.Chem., 268:17651-17654, 1993; PubMed: 8102368

Experimental method

X-RAY DIFFRACTION (2.9 Å)