8X91
P/Q type calcium channel in complex with omega-conotoxin MVIIC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Voltage-dependent L-type calcium channel subunit beta-3 | polymer | 496 | 56231.6 | 1 | UniProt (P54284) Pfam (PF12052) Pfam (PF00625) In PDB | Homo sapiens (human) | CAB3,Calcium channel voltage-dependent subunit beta 3 |
| 2 | X | Omega-conotoxin MVIIC | polymer | 26 | 2763.3 | 1 | UniProt (P37300) In PDB | Conus magus | Omega-CgTxMVIIC,SNX-230 |
| 3 | B | Voltage-dependent calcium channel subunit alpha-2/delta-1 | polymer | 1115 | 126316.1 | 1 | UniProt (P54289) Pfam (PF08399) Pfam (PF00092) Pfam (PF08473) In PDB | Homo sapiens (human) | Voltage-gated calcium channel subunit alpha-2/delta-1 |
| 4 | A | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | polymer | 2549 | 287534.3 | 1 | UniProt (O00555) Pfam (PF00520) Pfam (PF16905) Pfam (PF08763) In PDB | Homo sapiens (human) | Brain calcium channel I,BI,Calcium channel,L type,alpha-1 polypeptide isoform 4,Voltage-gated calcium channel subunit alpha Cav2.1 |
| 5 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB GlyTouCan (G47362BJ) | |||
| 6 | F, H, I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 7 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 830.8 | 1 | In PDB GlyTouCan (G01361SX) | |||
| 8 | B, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 9 | B, A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 10 | A | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 11 | A | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 1 | Chemie (PT5) | |||
| 12 | A | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
| 13 | A | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 2 | Chemie (3PE) |
Sequence modifications
C: 1 - 484 (UniProt: P54284)
B: 1 - 1103 (UniProt: P54289)
A: 1 - 2506 (UniProt: O00555)
| PDB | External Database | Details |
|---|---|---|
| Leu 485 | - | expression tag |
| Glu 486 | - | expression tag |
| His 487 | - | expression tag |
| His 488 | - | expression tag |
| His 489 | - | expression tag |
| His 490 | - | expression tag |
| His 491 | - | expression tag |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
| His 495 | - | expression tag |
| His 496 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 1104 | - | expression tag |
| Glu 1105 | - | expression tag |
| His 1106 | - | expression tag |
| His 1107 | - | expression tag |
| His 1108 | - | expression tag |
| His 1109 | - | expression tag |
| His 1110 | - | expression tag |
| His 1111 | - | expression tag |
| His 1112 | - | expression tag |
| His 1113 | - | expression tag |
| His 1114 | - | expression tag |
| His 1115 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -42 | - | initiating methionine |
| Ala -41 | - | expression tag |
| Ser -40 | - | expression tag |
| Trp -39 | - | expression tag |
| Ser -38 | - | expression tag |
| His -37 | - | expression tag |
| Pro -36 | - | expression tag |
| Gln -35 | - | expression tag |
| Phe -34 | - | expression tag |
| Glu -33 | - | expression tag |
| Lys -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ala -28 | - | expression tag |
| Arg -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Trp -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Phe -14 | - | expression tag |
| Glu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 472845.4 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2731.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6499.3 | |
| All* | Total formula weight | 482076.3 |
