8X90

P/Q type calcium channel

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	polymer	2549	287534.3	1	UniProt (O00555) Pfam (PF00520) Pfam (PF16905) Pfam (PF08763) In PDB	Homo sapiens (human)	Brain calcium channel I,BI,Calcium channel,L type,alpha-1 polypeptide isoform 4,Voltage-gated calcium channel subunit alpha Cav2.1
2	B	Voltage-dependent calcium channel subunit alpha-2/delta-1	polymer	1115	126316.1	1	UniProt (P54289) Pfam (PF08399) Pfam (PF00092) Pfam (PF08473) In PDB	Homo sapiens (human)	Voltage-gated calcium channel subunit alpha-2/delta-1
3	C	Voltage-dependent L-type calcium channel subunit beta-3	polymer	496	56231.6	1	UniProt (P54284) Pfam (PF12052) Pfam (PF00625) In PDB	Homo sapiens (human)	CAB3,Calcium channel voltage-dependent subunit beta 3
4	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	1	In PDB GlyTouCan (G47362BJ)
5	E, G, H	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
6	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		830.8	1	In PDB GlyTouCan (G01361SX)
7	A	1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]	non-polymer		566.6	1	Chemie (PS1)
8	A	CHOLESTEROL	non-polymer		386.7	5	Chemie (CLR)
9	A	[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate	non-polymer		1047.1	1	Chemie (PT5)
10	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
11	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
12	A	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	3	Chemie (Y01)
13	A	1,2-Distearoyl-sn-glycerophosphoethanolamine	non-polymer		748.1	2	Chemie (3PE)

Sequence modifications

A: 1 - 2506 (UniProt: O00555)

PDB	External Database	Details
Met -42	-	initiating methionine
Ala -41	-	expression tag
Ser -40	-	expression tag
Trp -39	-	expression tag
Ser -38	-	expression tag
His -37	-	expression tag
Pro -36	-	expression tag
Gln -35	-	expression tag
Phe -34	-	expression tag
Glu -33	-	expression tag
Lys -32	-	expression tag
Gly -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Ala -28	-	expression tag
Arg -27	-	expression tag
Gly -26	-	expression tag
Gly -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Trp -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
Pro -16	-	expression tag
Gln -15	-	expression tag
Phe -14	-	expression tag
Glu -13	-	expression tag
Lys -12	-	expression tag
Gly -11	-	expression tag
Phe -10	-	expression tag
Asp -9	-	expression tag
Tyr -8	-	expression tag
Lys -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Lys -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag

B: 1 - 1103 (UniProt: P54289)

PDB	External Database	Details
Leu 1104	-	expression tag
Glu 1105	-	expression tag
His 1106	-	expression tag
His 1107	-	expression tag
His 1108	-	expression tag
His 1109	-	expression tag
His 1110	-	expression tag
His 1111	-	expression tag
His 1112	-	expression tag
His 1113	-	expression tag
His 1114	-	expression tag
His 1115	-	expression tag

C: 1 - 484 (UniProt: P54284)

PDB	External Database	Details
Leu 485	-	expression tag
Glu 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag
His 492	-	expression tag
His 493	-	expression tag
His 494	-	expression tag
His 495	-	expression tag
His 496	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	470082.0
Branched	Number of molecules	5
	Total formula weight	2731.6
Non-Polymers*	Number of molecules	16
	Total formula weight	7025.9
All*	Total formula weight	479839.5

*Water molecules are not included.