8W85
HLA-DQ2.5-gamma2 gliadin peptide in complex with DQN0385AE01
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | DQN0385AE01 Fab heavy chain | polymer | 223 | 23810.7 | 2 | Homo sapiens (Human) | ||
2 | B, F | DQN0385AE01 Fab light chain | polymer | 213 | 23269.8 | 2 | Homo sapiens (Human) | ||
3 | C, G | HLA class II histocompatibility antigen, DQ alpha 1 chain | polymer | 189 | 21396.9 | 2 | UniProt (P01909) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | DC-1 alpha chain,DC-alpha,HLA-DCA,MHC class II DQA1 |
4 | D, H | MHC class II HLA-DQ-beta-1 - gamma2 gliadin peptide chimeric protein | polymer | 222 | 25386.6 | 2 | UniProt (O19712) Pfam (PF00969) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
5 | C, G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
C, G: 1 - 183 (UniProt: P01909)
D, H: 0 - 10 (PDB: 8W85)
D, H: 1001 - 1190 (UniProt: O19712)
PDB | External Database | Details |
---|---|---|
Ser 47 | Cys 70 | engineered mutation |
Leu 184 | - | expression tag |
Glu 185 | - | expression tag |
Val 186 | - | expression tag |
Leu 187 | - | expression tag |
Phe 188 | - | expression tag |
Gln 189 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 986 | - | linker |
Gly 987 | - | linker |
Gly 988 | - | linker |
Gly 989 | - | linker |
Ser 990 | - | linker |
Ile 991 | - | linker |
Glu 992 | - | linker |
Gly 993 | - | linker |
Arg 994 | - | linker |
Gly 995 | - | linker |
Ser 996 | - | linker |
Gly 997 | - | linker |
Gly 998 | - | linker |
Gly 999 | - | linker |
Ser 1000 | - | linker |
PDB | External Database | Details |
---|---|---|
Leu 1191 | - | expression tag |
Glu 1192 | - | expression tag |
Val 1193 | - | expression tag |
Leu 1194 | - | expression tag |
Phe 1195 | - | expression tag |
Gln 1196 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 187728.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 188170.6 |