8VRJ
Rigid body fitted model for gamma tubulin ring complex capped microtubule
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | 1, O, P, Q, R... | Tubulin alpha-1B chain | polymer | 457 | 51019.3 | 13 | UniProt (P68363) Pfam (PF00091) Pfam (PF03953) In PDB | Homo sapiens (human) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | 2, o, p, q, r... | Tubulin beta-3 chain | polymer | 456 | 51276.4 | 13 | UniProt (Q13509) Pfam (PF00091) Pfam (PF03953) In PDB | Homo sapiens (human) | Tubulin beta-4 chain,Tubulin beta-III |
| 3 | 3, 6, L | TUBGCP6 protein | polymer | 1811 | 199732.5 | 3 | UniProt (B2RWN4) Pfam (PF19340) Pfam (PF17681) Pfam (PF04130) In PDB | Homo sapiens (human) | |
| 4 | 5, B, D, F, H... | Gamma-tubulin complex component 3 | polymer | 907 | 103710.1 | 6 | UniProt (Q96CW5) Pfam (PF17681) Pfam (PF04130) In PDB | Homo sapiens (human) | hGCP3,Gamma-ring complex protein 104 kDa,hGrip104,Spindle pole body protein Spc98 homolog,hSpc98 |
| 5 | 7, 8 | Mitotic-spindle organizing protein 1 | polymer | 82 | 8485.7 | 2 | UniProt (Q08AG7) Pfam (PF12554) In PDB | Homo sapiens (human) | Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1 |
| 6 | 9 | Actin, cytoplasmic 1 | polymer | 375 | 41782.7 | 1 | UniProt (P60709) Pfam (PF00022) In PDB | Homo sapiens (human) | Beta-actin |
| 7 | A, C, E, G, M | Isoform 3 of Gamma-tubulin complex component 2 | polymer | 930 | 105581.5 | 5 | UniProt (Q9BSJ2) Pfam (PF17681) Pfam (PF04130) In PDB | Homo sapiens (human) | GCP-2,hGCP2,Gamma-ring complex protein 103 kDa,h103p,hGrip103,Spindle pole body protein Spc97 homolog,hSpc97 |
| 8 | I, K | Isoform 2 of Gamma-tubulin complex component 4 | polymer | 666 | 76108.9 | 2 | UniProt (Q9UGJ1) Pfam (PF17681) Pfam (PF04130) In PDB | Homo sapiens (human) | GCP-4,hGCP4,Gamma-ring complex protein 76 kDa,h76p,hGrip76 |
| 9 | J | Gamma-tubulin complex component 5 | polymer | 1024 | 118367.4 | 1 | UniProt (Q96RT8) Pfam (PF17681) Pfam (PF04130) In PDB | Homo sapiens (human) | GCP-5 |
| 10 | a, b, c, d, e... | Tubulin gamma-1 chain | polymer | 457 | 52022.6 | 14 | UniProt (P23258) Pfam (PF00091) Pfam (PF03953) In PDB | Homo sapiens (human) | Gamma-1-tubulin,Gamma-tubulin complex component 1,GCP-1 |
Sequence modifications
1, O, P, Q, R, S, T, U, V, W, X, Y, Z: 1 - 451 (UniProt: P68363)
2, o, p, q, r, s, t, u, v, w, x, y, z: 1 - 450 (UniProt: Q13509)
A, C, E, G, M: 1 - 930 (UniProt: Q9BSJ2)
J: 1 - 1024 (UniProt: Q96RT8)
a, b, c, d, e, f, g, h, i, j, k, l, m, n: 1 - 451 (UniProt: P23258)
| PDB | External Database | Details |
|---|---|---|
| His 37 | - | insertion |
| His 37 | - | insertion |
| His 37 | - | insertion |
| His 37 | - | insertion |
| His 37 | - | insertion |
| His 37 | - | insertion |
| Asp 254 | Glu 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 451 | - | expression tag |
| Asn 452 | - | expression tag |
| Leu 453 | - | expression tag |
| Tyr 454 | - | expression tag |
| Phe 455 | - | expression tag |
| Gln 456 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 209 | Arg 209 | conflict |
| Ser 211 | Asn 211 | conflict |
| Gly 229 | Asn 229 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 198 | Arg 198 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 452 | - | expression tag |
| Asn 453 | - | expression tag |
| Leu 454 | - | expression tag |
| Tyr 455 | - | expression tag |
| Phe 456 | - | expression tag |
| Gln 457 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 60 |
| Total formula weight | 4136865.2 | |
| All* | Total formula weight | 4136865.2 |
