8V08

Crystal structure of human PLD4 co-crystallized with 5'Pi-ssDNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	5'-3' exonuclease PLD4	polymer	488	53755.2	1	UniProt (Q96BZ4) Pfam (PF13918) In PDB	Homo sapiens (human)	Choline phosphatase 4,Phosphatidylcholine-hydrolyzing phospholipase D4,Phospholipase D family member 4,Phospholipase D4,PLD 4
2	B	5'-3' exonuclease PLD4	polymer	488	53676.2	1	UniProt (Q96BZ4) Pfam (PF13918) In PDB	Homo sapiens (human)	Choline phosphatase 4,Phosphatidylcholine-hydrolyzing phospholipase D4,Phospholipase D family member 4,Phospholipase D4,PLD 4
3	C, D	ssDNA	polymer	3	867.6	2		Homo sapiens

Sequence modifications

A: 60 - 506 (UniProt: Q96BZ4)

PDB	External Database	Details
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
Gly 25	-	expression tag
Pro 26	-	expression tag
Leu 27	-	expression tag
Val 28	-	expression tag
Asp 29	-	expression tag
Val 30	-	expression tag
Ala 31	-	expression tag
Ser 32	-	expression tag
Asn 33	-	expression tag
Glu 34	-	expression tag
Gln 35	-	expression tag
Lys 36	-	expression tag
Leu 37	-	expression tag
Ile 38	-	expression tag
Ser 39	-	expression tag
Glu 40	-	expression tag
Glu 41	-	expression tag
Asp 42	-	expression tag
Leu 43	-	expression tag
Ala 44	-	expression tag
Ser 45	-	expression tag
Met 46	-	expression tag
Thr 47	-	expression tag
Gly 48	-	expression tag
Gly 49	-	expression tag
Gln 50	-	expression tag
Gln 51	-	expression tag
Met 52	-	expression tag
Gly 53	-	expression tag
Arg 54	-	expression tag
Asp 55	-	expression tag
Ile 56	-	expression tag
Glu 57	-	expression tag
Gly 58	-	expression tag
Arg 59	-	expression tag

B: 60 - 506 (UniProt: Q96BZ4)

PDB	External Database	Details
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
Gly 25	-	expression tag
Pro 26	-	expression tag
Leu 27	-	expression tag
Val 28	-	expression tag
Asp 29	-	expression tag
Val 30	-	expression tag
Ala 31	-	expression tag
Ser 32	-	expression tag
Asn 33	-	expression tag
Glu 34	-	expression tag
Gln 35	-	expression tag
Lys 36	-	expression tag
Leu 37	-	expression tag
Ile 38	-	expression tag
Ser 39	-	expression tag
Glu 40	-	expression tag
Glu 41	-	expression tag
Asp 42	-	expression tag
Leu 43	-	expression tag
Ala 44	-	expression tag
Ser 45	-	expression tag
Met 46	-	expression tag
Thr 47	-	expression tag
Gly 48	-	expression tag
Gly 49	-	expression tag
Gln 50	-	expression tag
Gln 51	-	expression tag
Met 52	-	expression tag
Gly 53	-	expression tag
Arg 54	-	expression tag
Asp 55	-	expression tag
Ile 56	-	expression tag
Glu 57	-	expression tag
Gly 58	-	expression tag
Arg 59	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	109166.6
All*	Total formula weight	109166.6

*Water molecules are not included.