8U99

Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine adduct)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cystathionine beta-lyase	polymer	403	44102.2	2	UniProt (A0A0H3FMF8) Pfam (PF01053) In PDB	Klebsiella aerogenes KCTC 2190
2	A, B	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	2	Chemie (PLP)
3	A, B	SERINE	non-polymer		105.1	2	Chemie (SER)
4	A, B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
5	A, B	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
6		water	water		18.0	583	Chemie (HOH)

Sequence modifications

A, B: 1 - 395 (UniProt: A0A0H3FMF8)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ile 244	Val 244	engineered mutation
Pro 360	Leu 360	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88204.5
Non-Polymers*	Number of molecules	9
	Total formula weight	1047.2
All*	Total formula weight	89251.7

*Water molecules are not included.