8TZ3
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, B | Sodium/nucleoside cotransporter | polymer | 715 | 79376.8 | 3 | UniProt (F1MGR1) Pfam (PF01773) Pfam (PF07670) Pfam (PF07662) In PDB | Bos taurus (cattle) | |
| 2 | A, C, B | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 3 | A, C, B | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 12 | Chemie (LBN) | |||
| 4 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, C, B: 1 - 697 (UniProt: F1MGR1)
| PDB | External Database | Details |
|---|---|---|
| Met -14 | - | initiating methionine |
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Lys -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Glu -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 698 | - | expression tag |
| Asn 699 | - | expression tag |
| Ser 700 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 238130.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 9258.9 | |
| All* | Total formula weight | 247389.2 |
