8TXN
Adaptive mechanism of collagen IV scaffold assembly in Drosophila: crystal structure of recombinant NC1 hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Collagen alpha-1(IV) chain, Collagen IV - chain Viking, Collagen alpha-1(IV) chain | polymer | 726 | 79694.2 | 2 | UniProt (P08120) UniProt (Q9VMV5) Pfam (PF01413) In PDB | Drosophila melanogaster (fruit fly) | |
| 2 | A, D | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
| 3 | A, D | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | A, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | A, D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 6 | A, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 7 | A, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 8 | D | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 9 | D | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 10 | water | water | 18.0 | 862 | Chemie (HOH) |
Sequence modifications
A, D: 0 - 229 (UniProt: P08120)
A, D: 2000 - 2229 (UniProt: P08120)
A, D: 1000 - 1229 (UniProt: Q9VMV5)
| PDB | External Database | Details |
|---|---|---|
| Ala -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Leu -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Tyr -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Thr -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 230 | - | linker |
| Ser 231 | - | linker |
| Ser 232 | - | linker |
| Ala 233 | - | linker |
| Ser 234 | - | linker |
| Ser 235 | - | linker |
| Gly 236 | - | linker |
| Gly 2230 | - | cloning artifact |
| Ser 2231 | - | cloning artifact |
| Gly 2232 | - | cloning artifact |
| Ser 2233 | - | cloning artifact |
| Gly 2234 | - | cloning artifact |
| Ser 2235 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 1230 | - | linker |
| Ser 1231 | - | linker |
| Ser 1232 | - | linker |
| Ala 1233 | - | linker |
| Ser 1234 | - | linker |
| Ser 1235 | - | linker |
| Gly 1236 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 159388.3 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 2467.9 | |
| All* | Total formula weight | 161856.2 |
