8T1O
AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | AP-2 complex subunit alpha-2 | polymer | 630 | 70573.3 | 1 | UniProt (P17427) Pfam (PF01602) In PDB | Mus musculus (house mouse) | 100 kDa coated vesicle protein C,Adaptor protein complex AP-2 subunit alpha-2,Adaptor-related protein complex 2 subunit alpha-2,Alpha-adaptin C,Alpha2-adaptin,Clathrin assembly protein complex 2 alpha-C large chain,Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit |
| 2 | B | AP-2 complex subunit beta | polymer | 591 | 66953.2 | 1 | UniProt (Q9DBG3) Pfam (PF01602) In PDB | Mus musculus (house mouse) | AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit |
| 3 | M | AP-2 complex subunit mu | polymer | 435 | 49726.6 | 1 | UniProt (P84091) Pfam (PF01217) Pfam (PF00928) In PDB | Mus musculus (house mouse) | AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein |
| 4 | S | AP-2 complex subunit sigma | polymer | 142 | 17038.7 | 1 | UniProt (P62743) Pfam (PF01217) In PDB | Mus musculus (house mouse) | Adaptor protein complex AP-2 subunit sigma,Adaptor-related protein complex 2 subunit sigma,Clathrin assembly protein 2 sigma small chain,Clathrin coat assembly protein AP17,Clathrin coat-associated protein AP17,Plasma membrane adaptor AP-2 17 kDa protein,Sigma-adaptin 3b,Sigma2-adaptin |
| 5 | P | Trans-Golgi network integral membrane protein TGN38 | polymer | 14 | 1723.0 | 1 | UniProt (P19814) In PDB | Rattus norvegicus (Norway rat) | |
| 6 | A | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 1 | Chemie (PIO) |
Sequence modifications
A: 1 - 621 (UniProt: P17427)
| PDB | External Database | Details |
|---|---|---|
| Glu 272 | - | insertion |
| Gly 622 | - | expression tag |
| Ser 623 | - | expression tag |
| Gly 624 | - | expression tag |
| Leu 625 | - | expression tag |
| Glu 626 | - | expression tag |
| Val 627 | - | expression tag |
| Leu 628 | - | expression tag |
| Phe 629 | - | expression tag |
| Gln 630 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 206014.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 746.6 | |
| All* | Total formula weight | 206761.4 |
