8RIW

T2R-TTL-1-L01 complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB	Bos taurus (cattle)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B, D	Tubulin beta-2B chain	polymer	445	49999.9	2	UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB	Bos taurus (cattle)
3	E	Stathmin-4	polymer	142	16787.1	1	UniProt (P63043) Pfam (PF00836) In PDB	Rattus norvegicus (Norway rat)	Stathmin-like protein B3,RB3
4	F	Tubulin tyrosine ligase	polymer	384	44378.5	1	UniProt (A0A8V0Z8P0) Pfam (PF03133) In PDB	Gallus gallus (chicken)
5	A, C	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	F, A, B, C, D	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
7	A, B, C	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
8	A, B	IMIDAZOLE	non-polymer		69.1	3	Chemie (IMD)
9	B, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
10	B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
11	B, D	(2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate	non-polymer		377.4	2	Chemie (A1H00)
12	C	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
13	F	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
14		water	water		18.0	142	Chemie (HOH)

Sequence modifications

E: 5 - 145 (UniProt: P63043)

PDB	External Database	Details
Met 3	-	initiating methionine
Ala 4	-	expression tag
-	Gly 75	deletion

F: 1 - 378 (UniProt: A0A8V0Z8P0)

PDB	External Database	Details
-	Ala 53	deletion
-	Glu 54	deletion
-	Met 55	deletion
-	Gln 56	deletion
-	Gln 57	deletion
-	Gln 58	deletion
-	Leu 59	deletion
-	Leu 60	deletion
-	Glu 61	deletion
-	Gly 62	deletion
-	Asp 63	deletion
-	Gln 64	deletion
-	Thr 65	deletion
-	Leu 66	deletion
-	Val 67	deletion
-	Leu 68	deletion
-	Ala 69	deletion
-	Ser 70	deletion
-	Ser 71	deletion
-	Thr 72	deletion
-	His 73	deletion
-	Pro 74	deletion
-	Glu 75	deletion
-	Ser 76	deletion
-	Val 77	deletion
-	Asp 78	deletion
-	Ser 79	deletion
-	Asp 80	deletion
-	Lys 81	deletion
-	Asn 82	deletion
-	His 83	deletion
-	Gly 84	deletion
-	Phe 85	deletion
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	261574.3
Non-Polymers*	Number of molecules	21
	Total formula weight	3969.2
All*	Total formula weight	265543.5

*Water molecules are not included.