8P2L
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1 | polymer | 728 | 81070.7 | 16 | UniProt (Q6SZW1) UniProt (Q86DA5) Pfam (PF07647) Pfam (PF13676) In PDB | Homo sapiens (human) | NADase SARM1,hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,MyD88-5,SAM domain-containing protein 2,Tir-1 homolog,HsTIR,NADase tir-1,Neuronal symmetry protein 2,SARM1 homolog,Sterile alpha and TIR motif-containing protein tir-1 |
2 | A, B, C, D, E... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) |
Sequence modifications
A, B, C, D, E, F, G, H, J, I, K, L, M, N, O, P: 26 - 562 (UniProt: Q6SZW1)
A, B, C, D, E, F, G, H, J, I, K, L, M, N, O, P: 563 - 726 (UniProt: Q86DA5)
PDB | External Database | Details |
---|---|---|
Met -1 | - | initiating methionine |
Ser 0 | - | expression tag |
Tyr 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
Asp 8 | - | expression tag |
Tyr 9 | - | expression tag |
Asp 10 | - | expression tag |
Ile 11 | - | expression tag |
Pro 12 | - | expression tag |
Thr 13 | - | expression tag |
Thr 14 | - | expression tag |
Glu 15 | - | expression tag |
Asn 16 | - | expression tag |
Leu 17 | - | expression tag |
Tyr 18 | - | expression tag |
Phe 19 | - | expression tag |
Gln 20 | - | expression tag |
Gly 21 | - | expression tag |
Ala 22 | - | expression tag |
Met 23 | - | expression tag |
Gly 24 | - | expression tag |
Ser 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 1297130.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 5307.4 | |
All* | Total formula weight | 1302437.9 |