8J8R
Structure of beta-arrestin2 in complex with M2Rpp
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Beta-arrestin-2 | polymer | 420 | 47217.7 | 3 | UniProt (P32120) Pfam (PF00339) Pfam (PF02752) In PDB | Bos taurus (cattle) | Arrestin beta-2,Arrestin-3 |
2 | D, H, M | Fab30 Heavy Chain | polymer | 237 | 25512.4 | 3 | Mus musculus | ||
3 | E, L, N | Fab30 Light Chain | polymer | 215 | 23435.1 | 3 | Mus musculus | ||
4 | G, U, V | Muscarinic acetylcholine receptor M2 | polymer | 18 | 2362.9 | 3 | UniProt (P08172) In PDB | Homo sapiens |
Sequence modifications
A, B, C: 1 - 420 (UniProt: P32120)
PDB | External Database | Details |
---|---|---|
Gly 17 | Cys 17 | engineered mutation |
Val 60 | Cys 60 | engineered mutation |
Cys 69 | Leu 69 | engineered mutation |
Ser 126 | Cys 126 | engineered mutation |
Leu 141 | Cys 141 | engineered mutation |
Val 151 | Cys 151 | engineered mutation |
Val 243 | Cys 243 | engineered mutation |
Val 252 | Cys 252 | engineered mutation |
Ser 270 | Cys 270 | engineered mutation |
Phe 278 | Leu 278 | engineered mutation |
Ala 280 | Ser 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 295584.0 | |
All* | Total formula weight | 295584.0 |