8HGB

Crystal structure of the CYP199A4 mutant F182G in complex with 3-hydroxy-4-methoxybenzoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cytochrome P450	polymer	420	45756.7	1	UniProt (Q2IU02) Pfam (PF00067) In PDB	Rhodopseudomonas palustris HaA2
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	4-methoxy-3-oxidanyl-benzoic acid	non-polymer		168.1	1	Chemie (L6X)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	528	Chemie (HOH)

Sequence modifications

A: 0 - 409 (UniProt: Q2IU02)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Gly 182	Phe 183	engineered mutation
Leu 410	-	expression tag
Glu 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45756.7
Non-Polymers*	Number of molecules	3
	Total formula weight	876.7
All*	Total formula weight	46633.4

*Water molecules are not included.