8GYE

Crystal Structure of the 4-1BB in complex with ZG033 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Tumor necrosis factor receptor superfamily member 9	polymer	174	18541.8	2	UniProt (Q07011) Pfam (PF00020) In PDB	Homo sapiens (Human)	4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA
2	B, E	ZG033 Fab H chain	polymer	220	23180.9	2		Homo sapiens
3	C, F	ZG033 Fab L chain	polymer	214	23443.0	2		Homo sapiens
4	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	E	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6		water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, D: 24 - 186 (UniProt: Q07011)

PDB	External Database	Details
Leu 187	-	expression tag
Glu 188	-	expression tag
Gly 189	-	expression tag
Gly 190	-	expression tag
Gly 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	130331.2
Non-Polymers*	Number of molecules	3
	Total formula weight	534.5
All*	Total formula weight	130865.7

*Water molecules are not included.