8GY6

Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	932	106781.0	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB	Severe acute respiratory syndrome coronavirus 2	Pol, RdRp, Non-structural protein 12, nsp12
2	B, D	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp8
3	C	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTC1) Pfam (PF08716) UniProt (by SIFTS) (P0DTD1) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp7
4	A	Gossypol	non-polymer		518.6	2	Chemie (GO3)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	159835.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1037.1
All*	Total formula weight	160873.0

*Water molecules are not included.