8GS8
cryo-EM structure of the human respiratory complex II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | polymer | 664 | 72786.5 | 1 | UniProt (P31040) Pfam (PF00890) Pfam (PF02910) In PDB | Homo sapiens (human) | Flavoprotein subunit of complex II,Fp |
| 2 | B | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | polymer | 280 | 31674.8 | 1 | UniProt (P21912) Pfam (PF13085) Pfam (PF13534) In PDB | Homo sapiens (human) | |
| 3 | C | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | polymer | 169 | 18632.2 | 1 | UniProt (Q99643) Pfam (PF01127) In PDB | Homo sapiens (human) | Integral membrane protein CII-3,QPs-1,QPs1,Succinate dehydrogenase complex subunit C,Succinate-ubiquinone oxidoreductase cytochrome B large subunit,CYBL |
| 4 | D | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | polymer | 159 | 17064.0 | 1 | UniProt (O14521) Pfam (PF05328) In PDB | Homo sapiens (human) | |
| 5 | A | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 6 | B | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 7 | B | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 8 | B | FE3-S4 CLUSTER | non-polymer | 295.8 | 1 | Chemie (F3S) | |||
| 9 | C | UBIQUINONE-1 | non-polymer | 250.3 | 1 | Chemie (UQ1) | |||
| 10 | D | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 11 | D | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 1 | Chemie (PEV) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140157.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3195.6 | |
| All* | Total formula weight | 143353.1 |
