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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8GRM

Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, EHistone H3polymer9811562.62UniProt (A0A6I9KHI6)
Pfam (PF00125)
UniProt (by SIFTS) (P68431)
In PDB		Homo sapiens (human)
2B, FHistone H4polymer859704.42UniProt (A0A3Q2SS86)
Pfam (PF15511)
UniProt (by SIFTS) (P62805)
In PDB		Homo sapiens (human)
3C, GHistone H2A type 1-B/Epolymer10911995.12UniProt (P04908)
Pfam (PF00125)
Pfam (PF16211)
In PDB		Homo sapiensHistone H2A.2,Histone H2A/a,Histone H2A/m
4DHistone H2B type 1-Kpolymer9610736.41UniProt (O60814)
Pfam (PF00125)
In PDB		Homo sapiensH2B K,HIRA-interacting protein 1
5HHistone H2B type 1-Kpolymer9510607.21UniProt (O60814)
Pfam (PF00125)
In PDB		Homo sapiens (human)H2B K,HIRA-interacting protein 1
6MCOMMD3 proteinpolymer10111865.11UniProt (Q6IB93)
Pfam (PF13923)
UniProt (by SIFTS) (P35226)
In PDB		Homo sapiens (human)
7NRing1Bpolymer10111530.51UniProt (Q99496)
Pfam (PF13923)
In PDB		Homo sapiens
8IDNA (144-MER)polymer14444217.21Homo sapiens
9JDNA (145-MER)polymer14544992.61Homo sapiens
10OUbiquitinpolymer768576.81UniProt (P0CG47)
Pfam (PF00240)
In PDB		Homo sapiens (human)
11PUbcH5bpolymer14616575.81Pfam (PF00179)
UniProt (by SIFTS) (P62837)
In PDB		Homo sapiens
12M, NZINC IONnon-polymer65.44Chemie (ZN)
Sequence modifications
N: 16 - 116 (UniProt: Q99496)
PDBExternal DatabaseDetails
Leu 76Ile 76conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains14
Total formula weight225625.6
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight225887.3
*Water molecules are not included.

221371

PDB entries from 2024-06-19

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