8GFE

Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z3261 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Lytic transglycosylase domain-containing protein	polymer	544	63644.7	1	UniProt (A0A3I4HTM2) Pfam (PF01464) In PDB	Campylobacter jejuni	Transglycosylase SLT domain-containing protein
2	A	~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-4,5-bis(oxidanyl)-2-[(4-oxidanylidene-3~{H}-pyrido[1,2-a]pyrimidin-2-yl)methoxy]oxan-3-yl]ethanamide	non-polymer		380.4	1	Chemie (ZH8)
3	A	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
4	A	DIMETHYL SULFOXIDE	non-polymer		78.1	3	Chemie (DMS)
5		water	water		18.0	77	Chemie (HOH)

Sequence modifications

A: 19 - 541 (UniProt: A0A3I4HTM2)

PDB	External Database	Details
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Ser 8	-	expression tag
Ser 9	-	expression tag
Gly 10	-	expression tag
Leu 11	-	expression tag
Val 12	-	expression tag
Pro 13	-	expression tag
Arg 14	-	expression tag
Gly 15	-	expression tag
Ser 16	-	expression tag
His 17	-	expression tag
Met 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63644.7
Non-Polymers*	Number of molecules	5
	Total formula weight	806.9
All*	Total formula weight	64451.5

*Water molecules are not included.