8G4L

Cryo-EM structure of the human cardiac myosin filament

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	BB, BA, BG, BH, BI...	Myosin-7	polymer	1935	223446.0	78	UniProt (P12883) Pfam (PF02736) Pfam (PF00063) Pfam (PF01576) In PDB	Homo sapiens (human)	Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta
2	BE, BF, ba, bb, bg...	Myosin light chain 3	polymer	195	21962.1	18	UniProt (P08590) In PDB	Homo sapiens (human)	Cardiac myosin light chain 1,CMLC1,Myosin light chain 1,slow-twitch muscle B/ventricular isoform,MLC1SB,Ventricular myosin alkali light chain,Ventricular myosin light chain 1,VLCl,Ventricular/slow twitch myosin alkali light chain,MLC-lV/sb, Essential light chain
3	bc, bd, bi, bj, bq...	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	polymer	166	18813.3	18	UniProt (P10916) Pfam (PF13499) In PDB	Homo sapiens (human)	MLC-2v,Cardiac myosin light chain 2,Myosin light chain 2,slow skeletal/ventricular muscle isoform,MLC-2s/v,Ventricular myosin light chain 2
4	bm, bn, am, an, m...	Titin	polymer	1084	119772.0	6	UniProt (Q8WZ42) Pfam (PF00041) Pfam (PF07679) In PDB	Homo sapiens (human)	Connectin,Rhabdomyosarcoma antigen MU-RMS-40.14
5	bo, ao, o	Myosin-binding protein C, cardiac-type	polymer	1274	140947.2	3	UniProt (Q14896) Pfam (PF07679) Pfam (PF18362) Pfam (PF00041) In PDB	Homo sapiens (human)	Cardiac MyBP-C,C-protein,cardiac muscle isoform

Contents of the asymmetric unit

Polymers	Number of chains	123
	Total formula weight	19304216.2
All*	Total formula weight	19304216.2

*Water molecules are not included.