Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8EJK

Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AA modified Guanine nucleotide-binding protein G(q) subunit alphapolymer23827638.51Homo sapiens (human)
2BGuanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF00400)
In PDB		Homo sapiens (human)Transducin beta chain 1
3CGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer829137.51UniProt (P59768)
Pfam (PF00631)
In PDB		Homo sapiens (human)G gamma-I
4EscFv16polymer31834930.91Homo sapiens (human)
5RFree fatty acid receptor 1polymer50154298.81UniProt (O14842)
Pfam (PF00001)
In PDB		Homo sapiens (human)G-protein coupled receptor 40
6R[(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acidnon-polymer524.61Chemie (2YB)
Sequence modifications
C: 2 - 71 (UniProt: P59768)
PDBExternal DatabaseDetails
Met -10-expression tag
Gly -9-expression tag
His -8-expression tag
His -7-expression tag
His -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
Gly 0-expression tag
Gly 1-expression tag
R: 2 - 300 (UniProt: O14842)
PDBExternal DatabaseDetails
Met -200-initiating methionine
Gly -199-expression tag
Lys -198-expression tag
Thr -197-expression tag
Ile -196-expression tag
Ile -195-expression tag
Ala -194-expression tag
Leu -193-expression tag
Ser -192-expression tag
Tyr -191-expression tag
Ile -190-expression tag
Phe -189-expression tag
Cys -188-expression tag
Leu -187-expression tag
Val -186-expression tag
Phe -185-expression tag
Ala -184-expression tag
Asp -183-expression tag
Tyr -182-expression tag
Lys -181-expression tag
Asp -180-expression tag
Asp -179-expression tag
Asp -178-expression tag
Asp -177-expression tag
Ala -176-expression tag
Glu -175-expression tag
Asn -174-expression tag
Leu -173-expression tag
Tyr -172-expression tag
Phe -171-expression tag
Gln -170-expression tag
Gly -169-expression tag
Asn -168-expression tag
Ile -167-expression tag
Phe -166-expression tag
Glu -165-expression tag
Met -164-expression tag
Leu -163-expression tag
Arg -162-expression tag
Ile -161-expression tag
Asp -160-expression tag
Glu -159-expression tag
Gly -158-expression tag
Leu -157-expression tag
Arg -156-expression tag
Leu -155-expression tag
Lys -154-expression tag
Ile -153-expression tag
Tyr -152-expression tag
Lys -151-expression tag
Asp -150-expression tag
Thr -149-expression tag
Glu -148-expression tag
Gly -147-expression tag
Tyr -146-expression tag
Tyr -145-expression tag
Thr -144-expression tag
Ile -143-expression tag
Gly -142-expression tag
Ile -141-expression tag
Gly -140-expression tag
His -139-expression tag
Leu -138-expression tag
Leu -137-expression tag
Thr -136-expression tag
Lys -135-expression tag
Ser -134-expression tag
Pro -133-expression tag
Ser -132-expression tag
Leu -131-expression tag
Asn -130-expression tag
Ala -129-expression tag
Ala -128-expression tag
Lys -127-expression tag
Ser -126-expression tag
Glu -125-expression tag
Leu -124-expression tag
Asp -123-expression tag
Lys -122-expression tag
Ala -121-expression tag
Ile -120-expression tag
Gly -119-expression tag
Arg -118-expression tag
Asn -117-expression tag
Thr -116-expression tag
Asn -115-expression tag
Gly -114-expression tag
Val -113-expression tag
Ile -112-expression tag
Thr -111-expression tag
Lys -110-expression tag
Asp -109-expression tag
Glu -108-expression tag
Ala -107-expression tag
Glu -106-expression tag
Lys -105-expression tag
Leu -104-expression tag
Phe -103-expression tag
Asn -102-expression tag
Gln -101-expression tag
Asp -100-expression tag
Val -99-expression tag
Asp -98-expression tag
Ala -97-expression tag
Ala -96-expression tag
Val -95-expression tag
Arg -94-expression tag
Gly -93-expression tag
Ile -92-expression tag
Leu -91-expression tag
Arg -90-expression tag
Asn -89-expression tag
Ala -88-expression tag
Lys -87-expression tag
Leu -86-expression tag
Lys -85-expression tag
Pro -84-expression tag
Val -83-expression tag
Tyr -82-expression tag
Asp -81-expression tag
Ser -80-expression tag
Leu -79-expression tag
Asp -78-expression tag
Ala -77-expression tag
Val -76-expression tag
Arg -75-expression tag
Arg -74-expression tag
Ala -73-expression tag
Ala -72-expression tag
Leu -71-expression tag
Ile -70-expression tag
Asn -69-expression tag
Met -68-expression tag
Val -67-expression tag
Phe -66-expression tag
Gln -65-expression tag
Met -64-expression tag
Gly -63-expression tag
Glu -62-expression tag
Thr -61-expression tag
Gly -60-expression tag
Val -59-expression tag
Ala -58-expression tag
Gly -57-expression tag
Phe -56-expression tag
Thr -55-expression tag
Asn -54-expression tag
Ser -53-expression tag
Leu -52-expression tag
Arg -51-expression tag
Met -50-expression tag
Leu -49-expression tag
Gln -48-expression tag
Gln -47-expression tag
Lys -46-expression tag
Arg -45-expression tag
Trp -44-expression tag
Asp -43-expression tag
Glu -42-expression tag
Ala -41-expression tag
Ala -40-expression tag
Val -39-expression tag
Asn -38-expression tag
Leu -37-expression tag
Ala -36-expression tag
Lys -35-expression tag
Ser -34-expression tag
Arg -33-expression tag
Trp -32-expression tag
Tyr -31-expression tag
Asn -30-expression tag
Gln -29-expression tag
Thr -28-expression tag
Pro -27-expression tag
Asn -26-expression tag
Arg -25-expression tag
Ala -24-expression tag
Lys -23-expression tag
Arg -22-expression tag
Val -21-expression tag
Ile -20-expression tag
Thr -19-expression tag
Thr -18-expression tag
Phe -17-expression tag
Arg -16-expression tag
Thr -15-expression tag
Gly -14-expression tag
Thr -13-expression tag
Trp -12-expression tag
Asp -11-expression tag
Ala -10-expression tag
Tyr -9-expression tag
Leu -8-expression tag
Glu -7-expression tag
Val -6-expression tag
Leu -5-expression tag
Phe -4-expression tag
Gln -3-expression tag
Gly -2-expression tag
Pro -1-expression tag
Glu 0-expression tag
Phe 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight163422.5
Non-Polymers*Number of molecules1
Total formula weight524.6
All*Total formula weight163947.1
*Water molecules are not included.

219869

PDB entries from 2024-05-15

PDB statisticsPDBj update infoContact PDBjnumon