8DK5
Structure of 187bp LIN28b nucleosome with site 0 mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B, F | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (human) | |
| 3 | C, G | Histone H2A type 2-C | polymer | 129 | 14017.4 | 2 | UniProt (Q16777) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | H2A-clustered histone 20,Histone H2A-GL101,Histone H2A/q |
| 4 | D, H | Histone H2B type 2-E | polymer | 126 | 13951.2 | 2 | UniProt (Q16778) Pfam (PF00125) In PDB | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
| 5 | K, N | Single-chain variable fragment | polymer | 265 | 29030.1 | 2 | Mus musculus | ||
| 6 | I | DNA (187-MER) | polymer | 187 | 58223.4 | 1 | GenBank (2225930) | Homo sapiens | |
| 7 | J | DNA (187-MER) | polymer | 187 | 57215.5 | 1 | GenBank (2225930) | Homo sapiens |
Sequence modifications
I: -9 - 177 (GenBank: 2225930)
J: -14 - 172 (GenBank: 2225930)
| PDB | External Database | Details |
|---|---|---|
| Da 6 | - | insertion |
| Dg 7 | Dt 34520 | conflict |
| Dg 9 | Dt 34518 | conflict |
| Da 10 | Dt 34517 | conflict |
| Dg 13 | Dc 34514 | conflict |
| - | Dt 34512 | deletion |
| PDB | External Database | Details |
|---|---|---|
| - | Da 34512 | deletion |
| Dc 150 | Dg 34514 | conflict |
| Dt 153 | Da 34517 | conflict |
| Dc 154 | Da 34518 | conflict |
| Dc 156 | Da 34520 | conflict |
| Dt 157 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 283099.7 | |
| All* | Total formula weight | 283099.7 |
