8DH4
T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, E, I, M | T7 RNA polymerase | polymer | 883 | 98984.2 | 4 | UniProt (P00573) Pfam (PF14700) Pfam (PF00940) In PDB | Escherichia phage T7 | DNA-directed RNA polymerase |
2 | A, F, J, N | Template strand DNA | polymer | 18 | 5510.6 | 4 | synthetic construct | ||
3 | C, G, K, O | RNA | polymer | 12 | 3851.4 | 4 | synthetic construct | ||
4 | D, H, L, P | Non-template strand DNA | polymer | 9 | 2666.8 | 4 | synthetic construct | ||
5 | B, E | (7P)-3-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-7-(thiophen-2-yl)-3H-imidazo[4,5-b]pyridine | non-polymer | 573.3 | 2 | Chemie (S96) | |||
6 | B, E | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 444051.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1195.2 | |
All* | Total formula weight | 445246.9 |