8DG7
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Endoribonuclease Dcr-1 | polymer | 2249 | 255733.8 | 1 | UniProt (Q9VCU9) Pfam (PF20930) Pfam (PF00271) Pfam (PF03368) Pfam (PF20931) Pfam (PF02170) Pfam (PF00636) Pfam (PF20932) In PDB | Drosophila melanogaster (fruit fly) | Protein dicer-1 |
| 2 | E | RNA (22-MER) | polymer | 21 | 6835.1 | 1 | Drosophila melanogaster | ||
| 3 | F | RNA (38-MER) | polymer | 38 | 11916.1 | 1 | Drosophila melanogaster | ||
| 4 | K | Loquacious, isoform B | polymer | 465 | 50149.9 | 1 | UniProt (Q9VJY9) Pfam (PF00035) In PDB | Drosophila melanogaster (fruit fly) | R3D1-L,RE14437p |
| 5 | A, E, F | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 6 | E | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 1 | Chemie (U5P) |
Sequence modifications
A: 1 - 2249 (UniProt: Q9VCU9)
| PDB | External Database | Details |
|---|---|---|
| Arg 134 | Ser 134 | conflict |
| Ser 205 | Thr 205 | conflict |
| Leu 416 | Met 416 | conflict |
| Ser 702 | Ala 702 | conflict |
| Cys 796 | Ser 796 | conflict |
| Val 1332 | Ala 1332 | conflict |
| Ala 1338 | Pro 1338 | conflict |
| Ile 1339 | Thr 1339 | conflict |
| Ile 1345 | Leu 1345 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 324634.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 518.6 | |
| All* | Total formula weight | 325153.5 |
