8CNC
Structure of compound 1 bound KMT9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methyltransferase N6AMT1 | polymer | 203 | 21804.1 | 1 | UniProt (Q9Y5N5) Pfam (PF05175) In PDB | Homo sapiens (human) | HemK methyltransferase family member 2,M.HsaHemK2P,Lysine N-methyltransferase 9,Methylarsonite methyltransferase N6AMT1,Protein N(5)-glutamine methyltransferase |
2 | B | Multifunctional methyltransferase subunit TRM112-like protein | polymer | 126 | 14272.4 | 1 | UniProt (Q9UI30) Pfam (PF03966) In PDB | Homo sapiens (human) | tRNA methyltransferase 112 homolog |
3 | A | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine | non-polymer | 424.5 | 1 | Chemie (6D6) | |||
4 | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
A: 13 - 214 (UniProt: Q9Y5N5)
B: 3 - 126 (UniProt: Q9UI30)
PDB | External Database | Details |
---|---|---|
Ser 12 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36076.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 424.5 | |
All* | Total formula weight | 36500.9 |