8C56
CpG specific M.MpeI methyltransferase crystallized in the presence of 2'-deoxy-5-methylzebularine (5mZ) and 5-methylcytosine containing dsDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cytosine-specific methyltransferase | polymer | 395 | 46238.9 | 1 | UniProt (Q8EVR5) Pfam (PF00145) In PDB | Malacoplasma penetrans HF-2 | |
| 2 | B | DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5PY)P*GP*CP*TP*GP*AP*A)-3') | polymer | 14 | 4248.8 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3') | polymer | 14 | 4325.8 | 1 | synthetic construct | ||
| 4 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | C | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | water | water | 18.0 | 412 | Chemie (HOH) |
Sequence modifications
A: 1 - 395 (UniProt: Q8EVR5)
| PDB | External Database | Details |
|---|---|---|
| Arg 68 | Gln 68 | conflict |
| Arg 71 | Lys 71 | conflict |
| Pro 295 | Ser 295 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54813.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 499.5 | |
| All* | Total formula weight | 55313.1 |
