8BE8
Crystal structure of SOS1-HRas-peptidomimetic4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | R | GTPase HRas | polymer | 186 | 21046.6 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
| 2 | S | Son of sevenless homolog 1 | polymer | 507 | 59348.8 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) In PDB | Homo sapiens (human) | SOS-1 |
| 3 | P | SOS1-HRas-peptidomimetic4 | polymer | 9 | 1110.3 | 1 | Synthetic construct | ||
| 4 | R, S | FORMIC ACID | non-polymer | 46.0 | 8 | Chemie (FMT) | |||
| 5 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
R: 1 - 166 (UniProt: P01112)
S: 564 - 1049 (UniProt: Q07889)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 543 | - | initiating methionine |
| Gly 544 | - | expression tag |
| Ser 545 | - | expression tag |
| Ser 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| Ser 553 | - | expression tag |
| Ser 554 | - | expression tag |
| Gly 555 | - | expression tag |
| Leu 556 | - | expression tag |
| Val 557 | - | expression tag |
| Pro 558 | - | expression tag |
| Arg 559 | - | expression tag |
| Gly 560 | - | expression tag |
| Ser 561 | - | expression tag |
| His 562 | - | expression tag |
| Met 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 81505.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 368.2 | |
| All* | Total formula weight | 81873.8 |
