8B69
Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Ral guanine nucleotide dissociation stimulator-like 2 | polymer | 100 | 10972.4 | 2 | UniProt (O15211) Pfam (PF00788) In PDB | Homo sapiens (human) | RalGDS-like 2,RalGDS-like factor,Ras-associated protein RAB2L |
| 2 | B, D | Isoform 2B of GTPase KRas | polymer | 170 | 19400.9 | 2 | UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) In PDB | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 3 | B, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | B, D | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) |
Sequence modifications
A, C: 643 - 740 (UniProt: O15211)
B, D: 1 - 169 (UniProt: P01116-2)
| PDB | External Database | Details |
|---|---|---|
| Ser 641 | - | expression tag |
| Met 642 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60746.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 61839.6 |
