8AG1
Crystal structure of a novel OX40 antibody
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L, l | Novel OX40 antibody light chain | polymer | 216 | 23610.2 | 2 | Homo sapiens (Human) | ||
2 | H, h | Novel OX40 antibody heavy chain | polymer | 240 | 26180.1 | 2 | Homo sapiens (Human) | ||
3 | A, a | Tumor necrosis factor receptor superfamily member 4 | polymer | 156 | 17027.0 | 2 | UniProt (P43489) Pfam (PF00020) In PDB | Homo sapiens (Human) | ACT35 antigen,OX40L receptor,TAX transcriptionally-activated glycoprotein 1 receptor |
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
5 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, a: 29 - 170 (UniProt: P43489)
PDB | External Database | Details |
---|---|---|
Leu 52 | Met 52 | conflict |
Met 171 | - | expression tag |
Asp 172 | - | expression tag |
Pro 173 | - | expression tag |
Gly 174 | - | expression tag |
Gly 175 | - | expression tag |
Ser 176 | - | expression tag |
His 177 | - | expression tag |
His 178 | - | expression tag |
His 179 | - | expression tag |
His 180 | - | expression tag |
His 181 | - | expression tag |
His 182 | - | expression tag |
His 183 | - | expression tag |
His 184 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 133634.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 133855.7 |