8A6W
Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, E | Steroid C26-monooxygenase | polymer | 418 | 46616.7 | 2 | UniProt (P9WPL5) Pfam (PF00067) In PDB | Mycobacterium tuberculosis H37Rv | Cholest-4-en-3-one C26-monooxygenase,Cholest-4-en-3-one C26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming],Cholesterol C26-monooxygenase,Cholesterol C26-monooxygenase [(25R)-3beta-hydroxycholest-5-en-26-oate forming],Cytochrome P450 142,Steroid C27-monooxygenase |
2 | B, E | (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE | non-polymer | 384.6 | 2 | Chemie (K2B) | |||
3 | B, E | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
4 | water | water | 18.0 | 502 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 398 (UniProt: P9WPL5)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93233.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2002.3 | |
All* | Total formula weight | 95235.7 |