8A43

Human RNA polymerase I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-directed RNA polymerase I subunit RPA1	polymer	1720	195069.0	1	UniProt (O95602) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Homo sapiens (human)	RNA polymerase I subunit A1,A190,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,RNA polymerase I 194 kDa subunit,RPA194
2	B	DNA-directed RNA polymerase I subunit RPA2	polymer	1135	128379.2	1	UniProt (Q9H9Y6) Pfam (PF00562) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF06883) In PDB	Homo sapiens (human)	RNA polymerase I subunit 2,DNA-directed RNA polymerase I 135 kDa polypeptide,RPA135
3	C	DNA-directed RNA polymerases I and III subunit RPAC1	polymer	346	39301.7	1	UniProt (O15160) Pfam (PF01193) Pfam (PF01000) In PDB	Homo sapiens (human)	RNA polymerases I and III subunit AC1,AC40,DNA-directed RNA polymerases I and III 40 kDa polypeptide,RPA40,RPA39,RPC40
4	E	DNA-directed RNA polymerases I, II, and III subunit RPABC1	polymer	210	24584.2	1	UniProt (P19388) Pfam (PF03871) Pfam (PF01191) In PDB	Homo sapiens (human)	RNA polymerases I,II,and III subunit ABC1,DNA-directed RNA polymerase II 23 kDa polypeptide,DNA-directed RNA polymerase II subunit E,RPB5 homolog,XAP4
5	F	DNA-directed RNA polymerases I, II, and III subunit RPABC2	polymer	127	14491.0	1	UniProt (P61218) Pfam (PF01192) In PDB	Homo sapiens (human)	RNA polymerases I,II,and III subunit ABC2,DNA-directed RNA polymerase II subunit F,DNA-directed RNA polymerases I,and III 14.4 kDa polypeptide,RPABC14.4,RPB14.4,RPB6 homolog,RPC15
6	H	DNA-directed RNA polymerases I, II, and III subunit RPABC3	polymer	150	17162.3	1	UniProt (P52434) Pfam (PF03870) In PDB	Homo sapiens (human)	RNA polymerases I,II,and III subunit ABC3,DNA-directed RNA polymerase II subunit H,DNA-directed RNA polymerases I,and III 17.1 kDa polypeptide,RPB17,RPB8 homolog,hRPB8
7	I	DNA-directed RNA polymerase I subunit RPA12	polymer	126	13917.7	1	UniProt (Q9P1U0) Pfam (PF01096) In PDB	Homo sapiens (human)	DNA-directed RNA polymerase I subunit H,Zinc ribbon domain-containing protein 1
8	J	DNA-directed RNA polymerases I, II, and III subunit RPABC5	polymer	67	7655.1	1	UniProt (P62875) Pfam (PF01194) In PDB	Homo sapiens (human)	RNA polymerases I,II,and III subunit ABC5,DNA-directed RNA polymerase III subunit L,RNA polymerase II 7.6 kDa subunit,RPB7.6,RPB10 homolog
9	K	DNA-directed RNA polymerases I and III subunit RPAC2	polymer	133	15259.2	1	UniProt (P0DPB6) Pfam (PF13656) Pfam (PF01193) In PDB	Homo sapiens (human)	RNA polymerases I and III subunit AC2,AC19,DNA-directed RNA polymerase I subunit D,RNA polymerase I 16 kDa subunit,RPA16,RPC16,hRPA19
10	L	DNA-directed RNA polymerases I, II, and III subunit RPABC4	polymer	58	7018.2	1	UniProt (P53803) Pfam (PF03604) In PDB	Homo sapiens (human)	RNA polymerases I,II,and III subunit ABC4,ABC10-alpha,DNA-directed RNA polymerase II subunit K,RNA polymerase II 7.0 kDa subunit,RPB7.0,RPB10alpha
11	N	DNA-directed RNA polymerase I subunit RPA49	polymer	419	47330.2	1	UniProt (Q9GZS1) Pfam (PF06870) In PDB	Homo sapiens (human)	RNA polymerase I subunit A49,DNA-directed RNA polymerase I subunit E,RNA polymerase I-associated factor 1,RNA polymerase I-associated factor 53
12	M	DNA-directed RNA polymerase I subunit RPA34	polymer	510	55065.5	1	UniProt (O15446) Pfam (PF08208) In PDB	Homo sapiens (human)	A34.5,Antisense to ERCC-1 protein,ASE-1,CD3-epsilon-associated protein,CD3E-associated protein,DNA-directed RNA polymerase I subunit G,RNA polymerase I-associated factor PAF49

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	565233.5
All*	Total formula weight	565233.5

*Water molecules are not included.