7Z36
Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta | polymer | 482 | 54755.5 | 2 | UniProt (P00720) UniProt (Q13263) UniProt (Q13263-2) Pfam (PF00959) Pfam (PF14634) Pfam (PF00643) In PDB | Homo sapiens (human) | Lysis protein,Lysozyme,Muramidase,TIF1-beta,E3 SUMO-protein ligase TRIM28,KRAB-associated protein 1,KAP-1,KRAB-interacting protein 1,KRIP-1,Nuclear corepressor KAP-1,RING finger protein 96,RING-type E3 ubiquitin transferase TIF1-beta,Tripartite motif-containing protein 28 |
2 | C, S | SMARCAD1 CUE1 domain | polymer | 73 | 8189.1 | 2 | UniProt (by SIFTS) (Q9H4L7) In PDB | Homo sapiens | |
3 | D | Zinc finger protein 93 | polymer | 70 | 8194.5 | 1 | UniProt (P35789) Pfam (PF01352) In PDB | Homo sapiens (human) | Zinc finger protein 505,Zinc finger protein HTF34 |
4 | A, B | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
A, B: 26 - 185 (UniProt: P00720)
A, B: 187 - 271 (UniProt: Q13263)
A, B: 272 - 482 (UniProt: Q13263-2)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Ser 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
Ser 11 | - | expression tag |
Gln 12 | - | expression tag |
Asp 13 | - | expression tag |
Pro 14 | - | expression tag |
Asn 15 | - | expression tag |
Ser 16 | - | expression tag |
Ser 17 | - | expression tag |
Ser 18 | - | expression tag |
Glu 19 | - | expression tag |
Asn 20 | - | expression tag |
Leu 21 | - | expression tag |
Tyr 22 | - | expression tag |
Phe 23 | - | expression tag |
Gln 24 | - | expression tag |
Gly 25 | - | expression tag |
Ala 186 | - | linker |
A, B: 272 - 482 (UniProt: Q13263-2)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 134083.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 523.3 | |
All* | Total formula weight | 134606.9 |