7YZ6
Molecular snapshots of drug release from tubulin: Dark (steady state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (cattle) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (cattle) | |
| 3 | F | Designed Ankyrin Repeat Protein (DARPIN) D1 | polymer | 169 | 18068.4 | 1 | synthetic construct | ||
| 4 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | B | Azo-Combretastatin A4 (cis) | non-polymer | 318.3 | 1 | Chemie (IBL) | |||
| 8 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118272.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1453.4 | |
| All* | Total formula weight | 119726.1 |
