7YEG
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1208 | 133781.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | E, J, M | Angiotensin-converting enzyme 2 | polymer | 597 | 69153.7 | 3 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) | Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15 |
3 | H, G, N | heavy chain of R1-32 Fab | polymer | 228 | 23840.7 | 3 | Homo sapiens | ||
4 | L, I, O | light chain of R1-32 Fab | polymer | 214 | 22382.6 | 3 | Homo sapiens | ||
5 | D, F, K, P, Q... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
6 | B, M, C, E, A... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) | |||
7 | M, E, J | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Gly 682 | Arg 682 | engineered mutation |
Ser 683 | Arg 683 | engineered mutation |
Ser 685 | Arg 685 | engineered mutation |
Pro 817 | Phe 817 | engineered mutation |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 747475.0 | |
Branched | Number of molecules | 6 |
Total formula weight | 2546.4 | |
Non-Polymers* | Number of molecules | 39 |
Total formula weight | 8159.7 | |
All* | Total formula weight | 758181.1 |