7XJ2
Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, C, A, D | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP | polymer | 1061 | 120865.4 | 4 | UniProt (B2KYM6) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) UniProt (by SIFTS) (Q8NET8) In PDB | Homo sapiens (human) | |
| 2 | B, C, A, D | N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide | non-polymer | 478.4 | 4 | Chemie (EQK) |
Sequence modifications
B, C, A, D: 1 - 791 (UniProt: B2KYM6)
B, C, A, D: 792 - 1061 (PDB: 7XJ2)
| PDB | External Database | Details |
|---|---|---|
| Ile 25 | Val 25 | conflict |
| Arg 117 | Gly 117 | conflict |
| Lys 246 | Arg 246 | conflict |
| Gly 247 | Glu 247 | conflict |
| Ser 573 | Gly 573 | conflict |
| Asn 772 | Asp 772 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 483461.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1913.8 | |
| All* | Total formula weight | 485375.4 |
