7XAB
Crystal structure of PDE4D catalytic domain complexed with compound 22d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 507 | 57859.5 | 2 | UniProt (Q08499) Pfam (PF18100) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE3,PDE43 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | 9-(cyclopropylmethoxy)-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5-(pyridin-4-ylmethoxy)pyrano[3,2-b]xanthen-6-one | non-polymer | 553.6 | 2 | Chemie (AWI) | |||
| 5 | water | water | 18.0 | 473 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115719.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1286.7 | |
| All* | Total formula weight | 117005.7 |
