7WYU
Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Sodium/potassium-transporting ATPase subunit alpha | polymer | 1028 | 113389.9 | 2 | UniProt (Q4H132) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) In PDB | Squalus acanthias (spiny dogfish) | |
| 2 | B, D | Na+,K+-ATPase beta subunit | polymer | 305 | 35176.1 | 2 | UniProt (C4IX13) Pfam (PF00287) In PDB | Squalus acanthias (spiny dogfish) | Sodium/potassium-transporting ATPase subunit beta-1 |
| 3 | G, E | FXYD domain-containing ion transport regulator | polymer | 94 | 10195.8 | 2 | UniProt (Q70Q12) Pfam (PF02038) In PDB | Squalus acanthias (spiny dogfish) | |
| 4 | F, K | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 2 | In PDB GlyTouCan (G82348BZ) | |||
| 5 | H, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1114.0 | 2 | In PDB GlyTouCan (G61751GZ) | |||
| 6 | I, M | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 2 | In PDB GlyTouCan (G42466VF) | |||
| 7 | J, N | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | C, A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 9 | C, A | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 10 | C, A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 11 | A, B, C, D | CHOLESTEROL | non-polymer | 386.7 | 8 | Chemie (CLR) | |||
| 12 | A, E, G, C | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 24 | Chemie (PCW) | |||
| 13 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 317523.7 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 6980.4 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 23139.1 | |
| All* | Total formula weight | 347643.1 |
