7WRF

Mouse TRPM8 in lipid nanodiscs in the presence of calcium, icilin and PI(4,5)P2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Transient receptor potential cation channel subfamily M member 8	polymer	1120	129542.2	4	UniProt (Q8R4D5) Pfam (PF18139) Pfam (PF00520) In PDB	Mus musculus (house mouse)	Long transient receptor potential channel 6,LTrpC-6,LTrpC6,Transient receptor potential p8,Trp-p8
2	A, B, C, D	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	A, B, C, D	Icilin	non-polymer		311.3	4	Chemie (KX7)

Sequence modifications

A, B, C, D: 1 - 1104 (UniProt: Q8R4D5)

PDB	External Database	Details
Leu 1105	-	expression tag
Glu 1106	-	expression tag
Gly 1107	-	expression tag
Gly 1108	-	expression tag
Ser 1109	-	expression tag
Ser 1110	-	expression tag
Gly 1111	-	expression tag
Gly 1112	-	expression tag
Trp 1113	-	expression tag
Ser 1114	-	expression tag
His 1115	-	expression tag
Pro 1116	-	expression tag
Gln 1117	-	expression tag
Phe 1118	-	expression tag
Glu 1119	-	expression tag
Lys 1120	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	518168.9
Non-Polymers*	Number of molecules	9
	Total formula weight	1428.5
All*	Total formula weight	519597.4

*Water molecules are not included.