7WKI

Structure of the ultra-affinity complex between CFH and a nanobody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Complement factor H	polymer	192	22124.0	1	UniProt (P08603) Pfam (PF00084) In PDB	Homo sapiens (human)	H factor 1
2	B	Anti-CFH nanobody (VHH)	polymer	142	15036.5	1		Vicugna pacos
3		water	water		18.0	25	Chemie (HOH)

Sequence modifications

A: 1046 - 1231 (UniProt: P08603)

PDB	External Database	Details
His 1232	-	expression tag
His 1233	-	expression tag
His 1234	-	expression tag
His 1235	-	expression tag
His 1236	-	expression tag
His 1237	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37160.5
All*	Total formula weight	37160.5

*Water molecules are not included.