7UTI

ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM BOUND STATE

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, D, E, F, G...	Actin, alpha skeletal muscle	polymer	377	42110.0	16	UniProt (P68135) Pfam (PF00022) In PDB	Oryctolagus cuniculus (rabbit)	Alpha-actin-1
2	e, f, W, b, i...	Tropomyosin alpha-1 chain	polymer	285	32789.7	8	UniProt (P09493) Pfam (PF00261) In PDB	Homo sapiens (human)	Alpha-tropomyosin,Tropomyosin-1
3	X, Y, c, d	Isoform 6 of Troponin T, cardiac muscle	polymer	288	34659.4	4	UniProt (P45379) Pfam (PF00992) In PDB	Homo sapiens (human)	TnTc,Cardiac muscle troponin T,cTnT
4	V, a	Troponin I, cardiac muscle	polymer	210	24058.7	2	UniProt (P19429) Pfam (PF11636) Pfam (PF00992) In PDB	Homo sapiens (human)	Cardiac troponin I
5	U, Z	Troponin C, slow skeletal and cardiac muscles	polymer	161	18419.5	2	UniProt (P63316) Pfam (PF13833) Pfam (PF13499) In PDB	Homo sapiens (human)	TN-C
6	M, N, O, C, P...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	16	Chemie (ADP)
7	M, N, O, C, P...	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG)
8	U, Z	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)

Sequence modifications

e, f, W, b, i, j, g, h: 1 - 284 (UniProt: P09493)

PDB	External Database	Details
Ace 0	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	32
	Total formula weight	1159670.7
Non-Polymers*	Number of molecules	38
	Total formula weight	7464.6
All*	Total formula weight	1167135.3

*Water molecules are not included.