7US5

X-ray crystal structure of GDP-D-glycero-D-manno-heptose 4,6-Dehydratase from Campylobacter jejuni

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	GDP-D-GLYCERO-D-MANNO-HEPTOSE 4,6-DEHYDRATASE	polymer	365	41608.3	4	UniProt (Q5M6Q7) Pfam (PF16363) In PDB	Campylobacter jejuni	GDP-mannose 4,6-dehydratase, GDP-D-GLYCERO-D-MANNO-HEPTOSE 4,6-DEHYDRATASE,SDR FAMILY
2	A, B, C, D	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
3	A, B, C, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
4	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5		water	water		18.0	937	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 345 (UniProt: Q5M6Q7)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	166433.2
Non-Polymers*	Number of molecules	14
	Total formula weight	4798.9
All*	Total formula weight	171232.2

*Water molecules are not included.