7UBO
Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor CCD-956
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bromodomain testis-specific protein | polymer | 110 | 13146.2 | 4 | UniProt (Q58F21) Pfam (PF00439) In PDB | Homo sapiens (human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | A, B, C, D | N-[(2R)-1-(methylamino)-3-{1-[(4-methyl-2-oxo-1,2-dihydroquinolin-6-yl)acetyl]piperidin-4-yl}-1-oxopropan-2-yl]-5-phenylpyridine-2-carboxamide | non-polymer | 565.7 | 4 | Chemie (MJN) | |||
| 3 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 477 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Leu 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52584.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2340.8 | |
| All* | Total formula weight | 54925.7 |
