7U4Z
The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at very low protein concentration
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1 | polymer | 155 | 17775.1 | 1 | UniProt (P41212) UniProt (Q13470) Pfam (PF02198) | Homo sapiens (human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,CD38 negative kinase 1 |
| 2 | B (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | C (A) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 2 - 76 (UniProt: P41212)
A: 79 - 155 (UniProt: Q13470)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 35 | Arg 80 | engineered mutation |
| Glu 67 | Val 112 | engineered mutation |
| Gly 77 | - | linker |
| Gly 78 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 99 | Cys 610 | engineered mutation |
| Ala 133 | Cys 644 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17775.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 39.1 | |
| All* | Total formula weight | 17814.2 |
