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7TC0

The structure of human ABCA1 in digitonin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AATP-binding cassette, sub-family A (ABC1), member 1polymer2270255655.01UniProt (B2RUU2)
Pfam (PF12698)
Pfam (PF00005)
UniProt (by SIFTS) (O95477)
In PDB
Homo sapiens (human)
2B2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3Cbeta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G89225LT)
4ACHOLESTEROLnon-polymer386.72Chemie (CLR)
5A2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence modifications
A: 1 - 2261 (UniProt: B2RUU2)
PDBExternal DatabaseDetails
Gly 2262-expression tag
Asp 2263-expression tag
Tyr 2264-expression tag
Lys 2265-expression tag
Asp 2266-expression tag
Asp 2267-expression tag
Asp 2268-expression tag
Asp 2269-expression tag
Lys 2270-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight255655.0
BranchedNumber of molecules2
Total formula weight1335.2
Non-Polymers*Number of molecules4
Total formula weight1215.7
All*Total formula weight258205.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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