7TBC
Crystal structure of Plasmepsin X from Plasmodium falciparum in complex with WM382
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Plasmepsin 10 | polymer | 377 | 42948.5 | 1 | UniProt (Q2KNW6) Pfam (PF00026) UniProt (by SIFTS) (Q8IAS0) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
5 | A | (4R)-4-[(2E)-4,4-diethyl-2-imino-6-oxo-1,3-diazinan-1-yl]-N-[(4S)-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-6-carboxamide | non-polymer | 504.6 | 1 | Chemie (I0L) | |||
6 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 212 - 573 (UniProt: Q2KNW6)
PDB | External Database | Details |
---|---|---|
Glu 574 | - | expression tag |
Asn 575 | - | expression tag |
Leu 576 | - | expression tag |
Tyr 577 | - | expression tag |
Phe 578 | - | expression tag |
Gln 579 | - | expression tag |
Gly 580 | - | expression tag |
His 581 | - | expression tag |
His 582 | - | expression tag |
His 583 | - | expression tag |
His 584 | - | expression tag |
His 585 | - | expression tag |
His 586 | - | expression tag |
His 587 | - | expression tag |
His 588 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42948.5 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1851.1 | |
All* | Total formula weight | 44799.6 |