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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7SYO

Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1218S rRNApolymer1870603100.91Oryctolagus cuniculus
2BuS2 (SA)polymer29532958.01UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein SA, 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
3CeS1polymer26430002.11UniProt (G1SS70)
Pfam (PF01015)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S3a
4D40S ribosomal protein S2polymer22124441.81UniProt (G1TUT9)
In PDB		Oryctolagus cuniculus (rabbit)
5FeS4 (S4 X isoform)polymer26329654.91UniProt (G1TK17)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
UniProt (by SIFTS) (G1TA47)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S4
6GuS7polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S5
7HeS6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)
UniProt (by SIFTS) (A0A5K1UJS7)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S6
8IeS7polymer43247356.21UniProt (G1SVB0)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S7
9JeS8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S8
10KuS4polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Oryctolagus cuniculus (rabbit)Ribosomal protein S9
11LeS10polymer14917156.91UniProt (G1TPV3)
Pfam (PF03501)
In PDB		Oryctolagus cuniculus (rabbit)
12MuS17polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S11
13NeS12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S12
14OuS15polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Oryctolagus cuniculus (rabbit)Ribosomal protein S13
15PuS11polymer16818134.01UniProt (G1U472)
Pfam (PF00411)
UniProt (by SIFTS) (G1T1F0)
In PDB		Oryctolagus cuniculus (rabbit)
16QuS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S15
17RuS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)
In PDB		Oryctolagus cuniculus (rabbit)Ribosomal protein S16
18TuS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S18
19UeS19polymer14516235.81UniProt (G1TN62)
Pfam (PF01090)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S19
20VuS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S20
21WeS21polymer839124.41UniProt (G1TM82)
Pfam (PF01249)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S21
22XuS8polymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
In PDB		Oryctolagus cuniculus (rabbit)40S Ribosomal protein S15a
23YuS12polymer14315844.71UniProt (G1SZ47)
Pfam (PF00164)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S23
24ZeS24polymer13115237.11UniProt (G1T3D8)
Pfam (PF01282)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S24
25aeS25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S25
26beS26polymer10111645.81UniProt (G1TFE8)
Pfam (PF01283)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S26
27ceS27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S27
28deS28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
In PDB		Oryctolagus cuniculus (rabbit)40S Ribosomal protein S28
29euS14polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S29
30feS30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S30
31geS31polymer18821431.71UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S27a, Ubiquitin carboxyl extension protein 80,Ubiquitin-40S ribosomal protein S27a
32hReceptor for Activated C Kinase 1 (RACK1)polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)
In PDB		Oryctolagus cuniculus (rabbit)
33neL41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
In PDB		Oryctolagus cuniculus (rabbit)60s ribosomal protein l41
34EuS3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Oryctolagus cuniculus (rabbit)Ribosomal protein S3
35SeS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S17
36zHCV IRESpolymer400128746.11GenBank (149384897)Hepatitis C virus (isolate 1)
37b, gZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
B: 1 - 295 (UniProt: G1TLT8)
PDBExternal DatabaseDetails
Thr 114Ala 114conflict
D: 58 - 278 (UniProt: G1TUT9)
PDBExternal DatabaseDetails
Met 73Val 50conflict
Ser 101Ala 78conflict
Gly 119Ala 96conflict
Arg 194His 171conflict
Met 215Leu 192conflict
Arg 227Trp 204conflict
Gly 228Ser 205conflict
F: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Arg 51Lys 51conflict
Thr 78Ala 78conflict
Val 156Met 156conflict
J: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
W: 1 - 83 (UniProt: G1TM82)
PDBExternal DatabaseDetails
Asn 3Ser 3conflict
Asp 4Asn 4conflict
Gln 33Pro 33conflict
Phe 50Ser 50conflict
Ala 75Ser 75conflict
Asp 76His 76conflict
Lys 81Gln 81conflict
b: 2 - 102 (UniProt: G1TFE8)
PDBExternal DatabaseDetails
Arg 28Cys 28conflict
Ala 56Val 56conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains36
Total formula weight1389652.4
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight1389783.2
*Water molecules are not included.

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PDB entries from 2024-05-15

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