7SCO

Structure of H1 influenza hemagglutinin bound to Fab 310-39G10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, G	Hemagglutinin HA1 chain	polymer	322	35932.3	3	UniProt (Q289M7) Pfam (PF00509) In PDB	Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
2	B, D, I	Hemagglutinin HA2 chain	polymer	231	26637.6	3	UniProt (Q289M7) Pfam (PF00509) In PDB	Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
3	H, E, J	310-39G10 Fab, Heavy Chain	polymer	119	12796.3	3		Homo sapiens
4	L, F, K	310-39G10 Fab, Light Chain	polymer	108	11680.0	3		Homo sapiens
5	M, N, O	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
6	G, A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG)

Sequence modifications

A, C, G: 5 - 326 (UniProt: Q289M7)

PDB	External Database	Details
Val 169	Ala 182	conflict
Asn 190	Asp 203	conflict
Asp 225	Asn 238	conflict
Trp 255	Arg 268	conflict

B, D, I: 330 - 507 (UniProt: Q289M7)

PDB	External Database	Details
Arg 327	-	expression tag
Glu 328	-	expression tag
Thr 329	-	expression tag
Tyr 508	-	expression tag
Ile 509	-	expression tag
Pro 510	-	expression tag
Glu 511	-	expression tag
Ala 512	-	expression tag
Pro 513	-	expression tag
Arg 514	-	expression tag
Asp 515	-	expression tag
Gly 516	-	expression tag
Gln 517	-	expression tag
Ala 518	-	expression tag
Tyr 519	-	expression tag
Val 520	-	expression tag
Arg 521	-	expression tag
Lys 522	-	expression tag
Asp 523	-	expression tag
Gly 524	-	expression tag
Glu 525	-	expression tag
Trp 526	-	expression tag
Val 527	-	expression tag
Leu 528	-	expression tag
Leu 529	-	expression tag
Ser 530	-	expression tag
Thr 531	-	expression tag
Phe 532	-	expression tag
Leu 533	-	expression tag
Gly 534	-	expression tag
Ser 535	-	expression tag
Gly 536	-	expression tag
Leu 537	-	expression tag
Asn 538	-	expression tag
Asp 539	-	expression tag
Ile 540	-	expression tag
Phe 541	-	expression tag
Glu 542	-	expression tag
Ala 543	-	expression tag
Gln 544	-	expression tag
Lys 545	-	expression tag
Ile 546	-	expression tag
Glu 547	-	expression tag
Trp 548	-	expression tag
His 549	-	expression tag
Glu 550	-	expression tag
Gly 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag
His 555	-	expression tag
His 556	-	expression tag
His 557	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	261138.3
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2654.5
All*	Total formula weight	265066.0

*Water molecules are not included.