7RZU
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with A942S mutation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | SARS-CoV-2 HR1 A942S linked to a scaffold,Spike protein S2' | polymer | 257 | 28775.1 | 3 | UniProt (B2J981) UniProt (P0DTC2) Pfam (PF00210) In PDB | Nostoc punctiforme (strain ATCC 29133 / PCC 73102) | |
2 | D, E, F | Spike protein S2' | polymer | 41 | 4422.9 | 3 | UniProt (P0DTC2) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) |
Sequence modifications
A, B, C: 742 - 915 (UniProt: B2J981)
A, B, C: 917 - 988 (UniProt: P0DTC2)
D, E, F: 1162 - 1201 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Met 732 | - | initiating methionine |
Ser 733 | - | expression tag |
His 734 | - | expression tag |
His 735 | - | expression tag |
His 736 | - | expression tag |
His 737 | - | expression tag |
His 738 | - | expression tag |
His 739 | - | expression tag |
Gly 740 | - | expression tag |
Ser 741 | - | expression tag |
Ala 916 | - | linker |
PDB | External Database | Details |
---|---|---|
Ser 942 | Ala 942 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 1161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 99593.8 | |
All* | Total formula weight | 99593.8 |