7RY9
S. CEREVISIAE CYP51 I471T mutant COMPLEXED WITH Voriconazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lanosterol 14-alpha demethylase | polymer | 539 | 61873.2 | 1 | UniProt (A6ZSR0) Pfam (PF00067) UniProt (by SIFTS) (P10614) In PDB | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) | |
| 2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | A | Voriconazole | non-polymer | 349.3 | 1 | Chemie (VOR) | |||
| 4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A: 1 - 530 (UniProt: A6ZSR0)
| PDB | External Database | Details |
|---|---|---|
| Thr 471 | Ile 471 | engineered mutation |
| Gly 531 | - | expression tag |
| Gly 532 | - | expression tag |
| Arg 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61873.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1160.0 | |
| All* | Total formula weight | 63033.2 |
